Hypocholesterolemic Alkaloids of Lentinus edodes (BERK.) SING. III. Preparation of Analogous Compounds related to Eritadenine

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Fractionation and purification of the polysaccharides with marked antitumor activity, especially lentinan, from Lentinus edodes (Berk.) Sing. (an edible mushroom).

Six polysaccharide preparations, lentinan, LC-11, LC-12, LC-13, EC-11, and EC-14, were isolated from the watersoluble extracts of Lentinus edodes (Berk.) Sing., an edible mushroom, by fractional precipitation with ethanol and cetyltrimethylammonium hydroxide, fractional solubilization with acetic acid, and diethylaminoethyl cellulose column chromatography. The first two polysaccharide preparati...

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The Extracellular Indolic Compounds of Lentinus edodes

In macrobasidial fungi, the properties of compounds of a phytohormonal nature, which are well known in higher plants and are intensively studied in soil associative microorganisms, are only described in an unsystematic manner and, apparently, to an insufficient degree. Auxins are the most studied group of phytohormonal substances. As an object of research, along with other mycological objects o...

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Accumulation of zinc by the lentinus edodes (Berk.) mycelium cultivated in submerged culture.

To obtain rich in organic forms of zinc extracts of Lentinus edodes, possessing putative higher immunostimulating properties than actually used, mycelia were cultivated in zinc(II) enriched media. Culture media were enriched in zinc in concentration ranging from 0 to 90 microg mL(-1), added to the medium before inoculation. Total zinc concentration in submerged cultivated mycelial biomass has b...

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Shiitake (Lentinus edodes)

Shiitake mushroom, the common Japanese name for Lentinus edodes (Fig. 1), derives from the mushroom associated with the shii tree (Castanopsis cuspidate Schottky) and take, the Japanese word for mushroom (Table 1). Because Japan is the world leader in production of this type of mushroom, the mushroom is now widely known by this name. These mushrooms are renowned in Far East countries (e.g., Jap...

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Lentinus edodes promotes fat removal in hypercholesterolemic mice

Lentinus (L.) edodes (shiitake mushroom) is used as a traditional medicine in Asia. One of the components of L. edodes, eritadenine (an adenosine analog alkaloid), has been shown to reduce cholesterol levels. The hypocholesterolemic action of eritadenine appears to be achieved through the modification of hepatic phospholipid metabolism. In the present study, the effects of L. edodes in a mouse ...

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 1972

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.20.1186